BDBM50083230 1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-piperidin-4-yl)-3-ethyl-1,3-dihydro-benzoimidazol-2-one::1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one::1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL357076::J-113397

SMILES CCn1c2ccccc2n([C@@H]2CCN(CC3CCCCCCC3)C[C@H]2CO)c1=O

InChI Key InChIKey=MBGVUMXBUGIIBQ-LEWJYISDSA-N

Data  9 KI  11 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083230   

TargetMu-type opioid receptor(Homo sapiens (Human))
Leicester Royal Infirmary

Curated by PDSP Ki Database
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataKi:  214nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Leicester Royal Infirmary

Curated by PDSP Ki Database
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataKi: >400nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu type opioid receptor expressed in CHO cell membranes by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Leicester Royal Infirmary

Curated by PDSP Ki Database
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  2.20E+3nMAssay Description:Binding affinity in CHO cells stably expressing cloned human Opioid receptor mu 1 by displacing diprenorphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Leicester Royal Infirmary

Curated by PDSP Ki Database
LigandPNGBDBM50083230(1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...)
Affinity DataIC50:  3.40E+3nMAssay Description:Displacement of [3H]diprenorphin from cloned human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed